A comprehensive web-based platform for pan-genome analysis and functional annotation
PanWSGA (Pan-Web Single Genome Analyzer) is a powerful web-based platform designed for single-genome pangenome analysis. It enables researchers to project a single bacterial genome onto a curated, species-level pangenome reference derived from more than 100,000 high-quality assemblies.
The platform integrates standardized reannotation, a custom classification engine, and a dedicated visualization module to deliver reproducible gene-category profiles and functional summaries within minutes. All computational steps run on the server—no installation, local dependencies, or computational infrastructure required.
Compare genomes against reference databases and classify genes into core, accessory, and unique categories
Automated annotation using eggNOG-mapper with COG categories and GO term assignment
Venn diagrams, COG pie charts, and gene distribution visualizations
Download results in multiple formats including Excel, FASTA, and images
PanWSGA has been successfully applied in diverse research contexts
Monitor the emergence and spread of resistance genes across bacterial populations by identifying unique resistance determinants and tracking their distribution in clinical isolates
Identify bacterial strains with unique biosynthetic gene clusters and novel secondary metabolite pathways to prioritize candidates for natural product screening
Quickly assess the virulence potential of clinical isolates by identifying unique virulence factors, toxins, and pathogenicity islands compared to reference genomes
Verify probiotic strain identity and discover unique mechanisms of action by comparing probiotic genomes against species pangenomes to identify strain-specific beneficial traits